Coccidiosis is a protozoan disease of almost universal importance in poultry industry. This protozoa causes severe economic loss because it can multiply in the intestinal tract resulting in intestinal lesions, bloody diarrhea and high mortality. The mainly control of coccidiosis is anticoccidial drug that may be accumulate in poultry products and increase development of drug resistance. Alternated strategies for controlling the disease are detergents and good sanitary environment that could decrease the number of oocysts contaminated in poultry house. In addition, various types of vaccine and phytotherapy can increase respondent of poultry’s immunity. New researches bring a lot of new strategies for controlling the disease such as recombinant vaccine, plant extraction and drug resistance in different Eimeria species cause changing trend to control and prevent coccidiosis in poultry in order to improve food safety in poultry products and decrease the cost of production in poultry industry.
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